The GHS Column Model as an aid to selecting substitute substances

GHS Column Model - cover page
Source: DGUV

Under the German Hazardous Substances Ordinance, firms are required to replace hazardous substances if possible with substances with a lower health risk. As an aid to the assessment of possible substitute substances, the Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA) has developed the Column Model. On the basis of just a small amount of information on the products in question, substitute substances can be assessed with the aid of this table.

The current version from 2020 already includes the amendments of the 12th CLP Adaptation Regulation 2019/521.


Dr Thomas Smola

Exposure and Risk Assessment

Tel: +49 30 13001 3140
Fax: +49 30 13001 38001