The aim of the study is an in vivo creation of axially vascularized and transplantable soft tissue flaps in a porcine model which enable stable coverage of calvarial defects with exposed bone and are comparable to traditional autologous free flaps. An in vivo creation of soft tissue flaps would avoid large scale tissue harvest from healthy donor sites which may result in functional impairments and prolonged rehabilitation.
-cross sectoral-Type of hazard:
rehabilitationDescription, key words:
Tissue Engineering, soft tissue free flaps