Modern MR-Diagnostics of upper extremity related nerve injuries – MODERN pilot study

Status:

ongoing

Aims:

Prospective evaluation of MR-Neurography for:

1. Specifity and sensitivity in diagnosis of acute traumatic peripheral nerve injuries in correlation with the current gold-standard diagnostics as physical examination, intraoperative result, nerve conduction studies and neurosonography
2. An evidence based and standardized diagnostic algorithm for MR-Neurography in acute, traumatic peripheral nerve injuries
3. Imaging quality and applicability in patients with plate osteosynthesis

Activities/Methods:

A prospective, clinical multicenter study in patients suffering from acute traumatic, upper extremity related peripheral nerve injury. Beyond the standard diagnostic and therapeutic procedure, additional MR-neurographic examinations will be conducted in the following intervals: within 96 h following diagnosis, after 4-8 weeks, after 6, 12, 18 and, as appropriate, 24months. Subsequently, the results will be correlated with the current clinical gold-standard diagnostics (physical examination, intraoperative result, nerve conduction studies and neurosonography). As a complementary approach, the applicability of MR-Neurography in patients with plate osteosynthesis of the humerus bone will be investigated in a collective without peripheral nerve injuries. This study is an interdisciplinary collaboration of the Department of Neuroradiology, University of Heidelberg and the Departments of Hand, Plastic and Reconstructive Surgery of the BG Trauma Center Ludwigshafen and Frankfurt.

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