Dr. Heiko Udo Käfferlein


  • Ph.D., Chemistry and Analytical Toxicology, Friedrich-Alexander-University of Erlangen, Germany, 2000
  • Postdoctoral Training, CIIT Centers for Health Research, NC, USA, 2000-2003


My research focus concerns the general use of biomarker-based approaches to assess exposure to carcinogenic and mutagenic compounds and to early detect disease with a more specific interest on bladder cancer after exposure to aromatic amines and polycyclic aromatic hydrocarbons. Two major areas in which I work include biomarkers of the internal dose and the identification of non-invasive bladder cancer-specific biomarkers in urine and their effective use in occupational and clinical health surveillance (see literature list).


  • AG ”Threshold Limits in Air” and ad-hoc AG “Categorization of Carcinogens” – Senate Commission for the Investigation of Chemical Compounds at the Workplace (MAK Commission), German Research Foundation (DFG)
  • AG “Reproductive Toxicity” – UA III, Committee of Hazardous Substances (AGS), Federal Ministry of Labor and Social Affairs (BMAS)
  • Committee “Biological Exposure Indices” – American Conference of Governmental Industrial Hygienists (ACGIH)
  • Federation of European Toxicologists & European Societies of Toxicology (EUROTOX)
  • German Society of Clinical and Experimental Pharmacology and Toxicology (DGPT)
  • German Society of Occupational, Social and Environmental Medicine (DGAUM)
  • International Bladder Cancer Network (IBCN)
  • International Society of Exposure Sciences (ISES)
  • Scientific Committee “Occupational Toxicology” (SCOT) and “Occupational Health in the Chemical Industry” (MEDICHEM) – International Commission of Occupational Health (ICOH)
  • Society of Toxicology (SOT)