Dermal Penetration and Absorption of Hazardous Chemicals

Project No. IPA 63

Status:

ongoing

Aims:

The resorption of hazardous substances via the skin and their penetration into the body can cause toxicologically relevant concentrations in the human body alone and in combination with inhalative resorption and other uptake mechanisms. Within the project, an assessment of dermal absorption and penetration will be possible by combining different in vivo and in vitro methods.

Activities/Methods:

Use of various methods to estimate dermal absorption and penetration (Franz chamber, microdialysis, exposure laboratory studies).

Last Update:

12 Apr 2024

Project

Financed by:
  • Deutsche Gesetzliche Unfallversicherung e. V. (DGUV)
Research institution(s):
  • Institut für Prävention und Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung - Institut der Ruhr-Universität Bochum (IPA)
Branche(s):

-cross sectoral-

Type of hazard:

dangerous substances, work-related health hazards

Catchwords:

toxicology, chemical working substances

Description, key words:

hazardous substances, skin resorption, skin penetration

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Further information