completed 12/2002
Validation of a modified SHE (Le Boeuf) for sensitive and specific assessment of carcinogenic potential of aromatic amine compounds.
Experiments, reproduction of the reported tests of Le Boeuf (five carcinogenic, five non-carcinogenic AA)
Testing of five cancerogenic and five non-cancerogenic aromatic amine compounds proved suitability and validity of the pH 6.7 SHE-Assay for screening.
-cross sectoral-
Type of hazard:dangerous substances
Catchwords:Toxikologie, Krebserregende Stoffe, Messverfahren
Description, key words:carcinogenic, amine, SHE