Carcinogenic potential of aromatic amine compounds

Project No. FFFF 0214

Status:

completed 12/2002

Aims:

Validation of a modified SHE (Le Boeuf) for sensitive and specific assessment of carcinogenic potential of aromatic amine compounds.

Activities/Methods:

Experiments, reproduction of the reported tests of Le Boeuf (five carcinogenic, five non-carcinogenic AA)

Results:

Testing of five cancerogenic and five non-cancerogenic aromatic amine compounds proved suitability and validity of the pH 6.7 SHE-Assay for screening.

Last Update:

12-Jan-2004

Project

Financed by:
  • Hauptverband der gewerblichen Berufsgenossenschaften (HVBG)
Research institution(s):
  • BASF AG Product Safety, Regulations, Toxicology & Ecology, Experimental Toxicology, Ludwigshafen
Branche(s):

-cross sectoral-

Type of hazard:

dangerous substances

Catchwords:

Toxikologie, Krebserregende Stoffe, Messverfahren

Description, key words:

carcinogenic, amine, SHE