Pilot study to assess the influence of shift work on health - Analysis of the influence of shift work to metabolomic concentration- and hormone profiles on nurses

Project No. FF-FP 0321

Status:

ongoing

Aims:

The aim of this work is the analysis of blood and urine samples of shift working nurses. The obtained profiles of metabolomics and hormone will be used to identify biomarkers effecting the health of nurses. To verify changes of biomarker samples metabolomics and hormone profiles of nurses without shift work will be gathered as comparison.

Activities/Methods:

For the metabolite concentration profiles, the samples will be measured by using targeted metabolomics approach based on the AbsoluteDQTM p150 kit (BIOCRATES Life Science AG, Innsbruck, Austria), allowing simultaneous quantification of 163 metabolites using flow injection analysis (FIA) mass spectrometry (MS). To compare the detected metabolome and hormone profiles, statistical and bioinformatical methods will be used.

Last Update:

09-Dec-2011

Project

Financed by:
  • Deutsche Gesetzliche Unfallversicherung e. V. (DGUV)
Research institution(s):
  • Institut für Prävention und Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung - Institut der Ruhr-Universität Bochum (IPA)
  • Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Branche(s):

health service

Type of hazard:

Arbeitsbedingte Erkrankungen, Arbeitsorganisation/-schutzmanagement

Catchwords:

Prävention, Arbeitszeit, Messverfahren

Description, key words:

night work, shift work, metabolome, hormone profiles, nurses