Drawing up a programme for the numerical simulation of electrophysiological processes in heart muscle cells

Project No. BG10 #017

Status:

completed 01/1997

Aims:

Electrical accidents can lead to irregular heart beats and heart chamber fibrillation. Goal: acquiring knowledge of the electrical processes in the cell membrane of the heart muscle

Activities/Methods:

Computer simulation of the electrical processes in the cell membrane of the heart muscle cell which is modelled as a 1-dimensional cable equation; drawing up a programme for the numerical simulation of the mathematical model, verification of the programme, visualisation of the results, extensive test calculations and parameter variations

Results:

Description of a complete numerical model of the cell chain with extensions for simulation of the intercalated disks; comparison of the calculated potential and current distribution for passive membranes with analytical solutions; action potentials will be calculated for a cell chain with 15 individual cells, external stimulation thresholds determined and the propagation rate relative to intercalated disk resistance established.

Publications:

Medizinisch-Technischer Bericht 1997. Best.-Nr.: IK1. Berufsgenossenschaft der Feinmechanik und Elektrotechnik, Köln

Last Update:

22-Aug-2000

Project

Financed by:
  • Berufsgenossenschaft der Feinmechanik und Elektrotechnik
Research institution(s):
  • PALLAS Gesellschaft für Parallele Anwendungen und Systeme mbH
Branche(s):

electrical engineering

Type of hazard:

electrical hazards

Catchwords:

Gesundheitliche Beeinträchtigungen und Störungen, physikalische Faktoren, Unfall

Description, key words:

Irregular heartbeats caused by electrical accidents